Details

Home Details


Basic information of MIR125A :

Official Symbol of Gene MIR125A
Species Homo sapiens
Entrez Gene ID 31505
Official Full Name microRNA 125a
Also known as MIRN125A; mir-125a; miRNA125A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000208008 MIM:611191; miRBase:MI0000469; AllianceGenome:HGNC:31505
Map Location 19q13.41
Drug Natalizumab
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 24852919
Year 2014
Title Blood miRNA expression pattern is a possible risk marker for natalizumab-associated progressive multifocal leukoencephalopathy in multiple sclerosis patients

Results of multiple sclerosis :

Result We found that the expression level of three miRNAs (let-7c, miR-125a-5p and miR-642) was affected after 6 months of therapy
Mechanism/pathway Natalizumab has shown its efficacy in reducing multiple sclerosis (MS) relapses and progression of disability