Basic information of IL1A :

Official Symbol of Gene	IL1A
Species	Homo sapiens
Entrez Gene ID	3552
Official Full Name	interleukin 1 alpha
Also known as	IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000115008 MIM:147760; AllianceGenome:HGNC:5991
Map Location	2q14.1
Drug	IFN-b treatment
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	12437583
Year	2002
Title	Modulation of astrocyte inducible nitric oxide synthase and cytokine expression by interferon beta is associated with induction and inhibition of interferon gamma-activated sequence binding activity

Results of multiple sclerosis :

Result	Northern blot analysis for TNF-a, IL-6 and iNOS demonstrated that IFN-b enhanced mRNA expression induced by IL-1 alone.
Mechanism/pathway	human fetal astrocytes revealed that IL-1-induced TNF-a, IL-6, as well as iNOS, are regulated by type-I and type-II IFNs.