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Basic information of IFNAR2 :

Official Symbol of Gene IFNAR2
Species Homo sapiens
Entrez Gene ID 5433
Official Full Name interferon alpha and beta receptor subunit 2
Also known as IFN-R; IMD45; IFNABR; IFNARB; IFN-R-2; IFN-alpha-REC
Gene Type protein coding
dbXrefs Ensembl:ENSG00000159110 MIM:602376; AllianceGenome:HGNC:5433
Map Location 21q22.11
Drug IFN-β
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 27346865
Year 2016
Title Immune response genes receptors expression and polymorphisms in relation to multiple sclerosis susceptibility and response to INF-β therapy

Results of multiple sclerosis :

Result There was a significant decrease of IFNAR1 and IFNAR2 mRNA expression and a significant increase of CCR5 mRNA expression in MS patients compared with the control group
Mechanism/pathway N/A