Basic information of Il4 :

Official Symbol of Gene	Il4
Species	Mus musculus
Entrez Gene ID	96556
Official Full Name	interleukin 4
Also known as	Il-4; BSF-1
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000000869 AllianceGenome:MGI:96556
Map Location	11 B1.3; 11 31.97 cM
Drug	Ad-IL4-MSCs
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57BL/6
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	22568986
Year	2012
Title	Early intervention with gene-modified mesenchymal stem cells overexpressing interleukin-4 enhances anti-inflammatory responses and functional recovery in experimental autoimmune demyelination

Results of multiple sclerosis :

Result	Notably, the early administration of Ad-IL4-MSCs in mice with EAE at the time of T-cell priming attenuated clinical disease
Mechanism/pathway	This protective effect was associated with a reduction in peripheral MOG-specific T-cell responses and a shift from a pro- to an anti-inflammatory cytokine response