Basic information of Ahr :

Official Symbol of Gene	Ahr
Species	Mus musculus
Entrez Gene ID	105043
Official Full Name	aryl-hydrocarbon receptor
Also known as	Ah; In; Ahh; Ahre; bHLHe76
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000019256 AllianceGenome:MGI:105043
Map Location	12 A3; 12 15.78 cM
Drug	Laquinimod
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57BL/6
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	33408169
Year	2021
Title	Aryl Hydrocarbon Receptor Activation in Astrocytes by Laquinimod Ameliorates Autoimmune Inflammation in the CNS

Results of multiple sclerosis :

Result	Laq Ameliorates Autoimmune CNS Inflammation Independent of AHR in Myeloid Cells
Mechanism/pathway	Laq administration led to the activation of AHR in astrocytes, which was associated with clinical improvement during late stages of EAE, reduction of CNS-infiltrating proinflammatory monocytes and T-cell numbers, and polarization