Basic information of Mmp9 :

Official Symbol of Gene	Mmp9
Species	Rattus norvegicus
Entrez Gene ID	621320
Official Full Name	matrix metallopeptidase 9
Also known as	N/A
Gene Type	protein coding
dbXrefs	Ensembl:ENSRNOG00000017539 AllianceGenome:RGD:621320
Map Location	3q42
Drug	Rolipram
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	Lewis rats
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	16182379
Year	2005
Title	Rolipram impairs NF-kappaB activity and MMP-9 expression in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result	Rolipram reduces the MMP-9 gene expression in LNCsand CNS from EAE animals
Mechanism/pathway	The available evidence points towards NF-nB inhibition as one of the key therapeutic mechanisms whichwould mediate down-regulation of genes codifying for proteins involved in cell migration