Details

Home Details


Basic information of Hmox1 :

Official Symbol of Gene Hmox1
Species Rattus norvegicus
Entrez Gene ID 2806
Official Full Name heme oxygenase 1
Also known as Ho1; Heox; Hmox; Ho-1; HEOXG; hsp32
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000014117 AllianceGenome:RGD:2806
Map Location 19p11
Drug Snpp-9
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent Wistar rats
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 15497037
Year 2004
Title [Dynamic changes of heme oxygenase-1 protein and mRNA in the brains of rats with experimental allergic encephalomyelitis]

Results of multiple sclerosis :

Result After a specific inhibitor of HO-1, Snpp-9, was applied, both of the symptoms and pathological lesions of EAE in the rat brains were mitigated markedly
Mechanism/pathway Antioxidant effect