Basic information of Il1b :

Official Symbol of Gene	Il1b
Species	Rattus norvegicus
Entrez Gene ID	2891
Official Full Name	interleukin 1 beta
Also known as	IL-1F2
Gene Type	protein coding
dbXrefs	Ensembl:ENSRNOG00000004649 AllianceGenome:RGD:2891
Map Location	3q36
Drug	Piperine
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	female Lewis rats
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	34338970
Year	2021
Title	Piperine Improves Experimental Autoimmune Encephalomyelitis (EAE) in Lewis Rats Through its Neuroprotective, Anti-inflammatory, and Antioxidant Effects

Results of multiple sclerosis :

Result	Gene expression analysis in lumbar spinal cord showed that piperine treatment decreased the level of pro-inflammatory cytokines (TNF-α, IL-1β) and iNOS and enhanced IL-10, Nrf2, HO-1, and MBP expressions
Mechanism/pathway	the efficiency of piperine on progression of EAE model and myelin repair mechanisms was investigated