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Basic information of TLR2 :

Official Symbol of Gene TLR2
Species Homo sapiens
Entrez Gene ID 11848
Official Full Name toll like receptor 2
Also known as TIL4; CD282
Gene Type protein coding
dbXrefs Ensembl:ENSG00000137462 MIM:603028; AllianceGenome:HGNC:11848
Map Location 4q31.3
Drug G2013
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 31594427
Year 2019
Title Effects of guluronic acid (G2013) on gene expression of TLR2, TLR4, MyD88, TNF-α and CD52 in multiple sclerosis under in vitro conditions

Results of multiple sclerosis :

Result Our research indicated that this drug could significantly decrease the gene expression of TLR2, TLR4 and TNF-α compared to untreated group
Mechanism/pathway reducing the pathological process