Basic information of Calca :

Official Symbol of Gene	Calca
Species	Mus musculus
Entrez Gene ID	12310
Official Full Name	calcitonin/calcitonin-related polypeptide, alpha
Also known as	CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000030669 AllianceGenome:MGI:2151253
Map Location	7 F1; 7 59.99 cM
Drug	Gene therapy with CGRP-expressing mDC
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57BL/6 mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	22807299
Year	2012
Title	Suppression of murine experimental autoimmune optic neuritis by mature dendritic cells transfected with calcitonin gene-related Peptide gene

Results of multiple sclerosis :

Result	The CGRP mRNA expression was also markedly and significantly upregulated in CGRP-transfected mDCs compared with the mock-transfected cells
Mechanism/pathway	CGRP augmented the LPS and GM-CSF–induced IL-10 expression but suppressed the LPS and GM-CSF-induced IL-1 and IL-12 expression.