Basic information of TLR4 :

Official Symbol of Gene	TLR4
Species	Homo sapiens
Entrez Gene ID	11850
Official Full Name	toll like receptor 4
Also known as	TOLL; CD284; TLR-4; ARMD10
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000136869 MIM:603030; AllianceGenome:HGNC:11850
Map Location	9q33.1
Drug	G2013
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	31594427
Year	2019
Title	Effects of guluronic acid (G2013) on gene expression of TLR2, TLR4, MyD88, TNF-α and CD52 in multiple sclerosis under in vitro conditions

Results of multiple sclerosis :

Result	Our research indicated that this drug could significantly decrease the gene expression of TLR2, TLR4 and TNF-α compared to untreated group
Mechanism/pathway	reducing the pathological process