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Basic information of TSC22D3 :

Official Symbol of Gene TSC22D3
Species Homo sapiens
Entrez Gene ID 3051
Official Full Name TSC22 domain family member 3
Also known as DIP; GILZ; DSIPI; TSC-22R
Gene Type protein coding
dbXrefs Ensembl:ENSG00000157514 MIM:300506; AllianceGenome:HGNC:3051
Map Location Xq22.3
Drug IVMP
Interaction Type activator

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 34593869
Year 2021
Title Methylprednisolone stimulated gene expression (GILZ, MCL-1) and basal cortisol levels in multiple sclerosis patients in relapse are associated with clinical response

Results of multiple sclerosis :

Result GILZ and MCL-1 gene expression were significantly higher following first IVMP treatment in responders, compared to non-responders
Mechanism/pathway Glucocorticoids (GCs) are the main treatment of relapse in multiple sclerosis (MS)