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Basic information of MCL1 :

Official Symbol of Gene MCL1
Species Homo sapiens
Entrez Gene ID 6943
Official Full Name MCL1 apoptosis regulator, BCL2 family member
Also known as TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT
Gene Type protein coding
dbXrefs Ensembl:ENSG00000143384 MIM:159552; AllianceGenome:HGNC:6943
Map Location 1q21.2
Drug IVMP
Interaction Type activator

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 34593869
Year 2021
Title Methylprednisolone stimulated gene expression (GILZ, MCL-1) and basal cortisol levels in multiple sclerosis patients in relapse are associated with clinical response

Results of multiple sclerosis :

Result GILZ and MCL-1 gene expression were significantly higher following first IVMP treatment in responders, compared to non-responders
Mechanism/pathway Glucocorticoids (GCs) are the main treatment of relapse in multiple sclerosis (MS)