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Basic information of GSTP1 :

Official Symbol of Gene GSTP1
Species Homo sapiens
Entrez Gene ID 4638
Official Full Name glutathione S-transferase pi 1
Also known as PI; DFN7; GST3; GSTP; FAEES3; HEL-S-22
Gene Type protein coding
dbXrefs Ensembl:ENSG00000084207 MIM:134660; AllianceGenome:HGNC:4638
Map Location 11q13.2
Drug Natalizumab
Interaction Type activator

Sample information of multiple sclerosis:

Descent N/A
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 27993870
Year 2016
Title Possible Implication of GSTP1 and NQO1 Polymorphisms on Natalizumab Response in Multiple Sclerosis

Results of multiple sclerosis :

Result Among our cohort of MS patients, 88.5% responded and 11.5% manifested clinical deterioration after natalizumab treatment
Mechanism/pathway oxidative stress reduction might be another mechanism through which natalizumab exerts its protective effect