Basic information of NQO1 :

Official Symbol of Gene	NQO1
Species	Homo sapiens
Entrez Gene ID	2874
Official Full Name	NAD(P)H quinone dehydrogenase 1
Also known as	DTD; QR1; DHQU; DIA4; NMOR1; NMORI
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000181019 MIM:125860; AllianceGenome:HGNC:2874
Map Location	16q22.1
Drug	Natalizumab
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	27993870
Year	2016
Title	Possible Implication of GSTP1 and NQO1 Polymorphisms on Natalizumab Response in Multiple Sclerosis

Results of multiple sclerosis :

Result	Among our cohort of MS patients, 88.5% responded and 11.5% manifested clinical deterioration after natalizumab treatment
Mechanism/pathway	oxidative stress reduction might be another mechanism through which natalizumab exerts its protective effect