Basic information of Il10 :

Official Symbol of Gene	Il10
Species	Mus musculus
Entrez Gene ID	96537
Official Full Name	interleukin 10
Also known as	CSIF; If2a; Il-10
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000016529 AllianceGenome:MGI:96537
Map Location	1 E4; 1 56.89 cM
Drug	XT-101-R
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	Male Dark Agouti rats
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	27189037
Year	2017
Title	Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy

Results of multiple sclerosis :

Result	XT-101-R reversed motor symptoms, and attenuated loss of body weight, the standard outcome measures for EAE.
Mechanism/pathway	IL-10 has the potential to decrease disease severity by decreasing expression of pro-inflammatory cytokines, decreasing antigen presentation, inducing T cell anergy and promoting neuroprotection