Basic information of Il10 :

Official Symbol of Gene	Il10
Species	Mus musculus
Entrez Gene ID	16153
Official Full Name	interleukin 10
Also known as	CSIF; If2a; Il-10
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000016529 AllianceGenome:MGI:96537
Map Location	1 E4; 1 56.89 cM
Drug	Gene therapy with CGRP-expressing mDC
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57BL/6 mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	22807299
Year	2012
Title	Suppression of murine experimental autoimmune optic neuritis by mature dendritic cells transfected with calcitonin gene-related Peptide gene

Results of multiple sclerosis :

Result	These findings indicate that IL-10 production is upregulated in CGRP-transfected mDC.
Mechanism/pathway	Furthermore, neutralization of IL-10 activity largely abrogated the suppressive effects of CGRP on B7-2 upregulation.