Basic information of Il10 :

Official Symbol of Gene	Il10
Species	Mus musculus
Entrez Gene ID	96537
Official Full Name	interleukin 10
Also known as	CSIF; If2a; Il-10
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000016529 AllianceGenome:MGI:96537
Map Location	1 E4; 1 56.89 cM
Drug	pVAXhsp65
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57BL/6
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	28321419
Year	2017
Title	pVAXhsp65 Vaccination Primes for High IL-10 Production and Decreases Experimental Encephalomyelitis Severity

Results of multiple sclerosis :

Result	Previous immunization with pVAXhsp65 significantly reduced EAE symptoms. Infiltrating cells from the CNS stimulated with rhsp65 produced significantly higher levels of IL-10.
Mechanism/pathway	IL-10 producer cells, specific for MOG35–55 or hsp65, had migrated to the CNS and partially controlled inflammation.