Basic information of RORC :
| Official Symbol of Gene | RORC |
| Species | Homo sapiens |
| Entrez Gene ID | 6097 |
| Official Full Name | RAR related orphan receptor C |
| Also known as | TOR; RORG; RZRG; IMD42; NR1F3; RZR-GAMMA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000143365 MIM:602943; AllianceGenome:HGNC:10260 |
| Map Location | 1q21.3 |
| Drug | EGCG |
| Interaction Type | inhibitor |
Sample information of multiple sclerosis:
| Descent | NA |
| Disease | MS |
Literature information of multiple sclerosis :
| Pubmed ID | 35154593 |
| Year | 2021 |
| Title | Evaluating the Effects of Epigallocatechin-3-Gallate on HIF-1α Protein and RORC Gene Expression in Peripheral Blood Mononuclear Cells in Patients With Multiple Sclerosis |
Results of multiple sclerosis :
| Result | However, EGCG did not influence the level of HIF-1α. Our present data has led us to conclude that EGCG could be considered as an anti-inflammatory agent may serve as an achievable therapeutic agent for MS. |
| Mechanism/pathway | Multiple Sclerosis (MS) is the chronic inflammation of the Central Nervous System (CNS) and autoimmune disease. |
