Basic information of SOD2 :

Official Symbol of Gene	SOD2
Species	Homo sapiens
Entrez Gene ID	6648
Official Full Name	superoxide dismutase 2
Also known as	GC1; IPOB; IPO-B; MNSOD; MVCD6; GClnc1; Mn-SOD
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000291237 MIM:147460; AllianceGenome:HGNC:11180
Map Location	6q25.3
Drug	melatonin treatment
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	Sina
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	26679105
Year	2016
Title	Evidence for possible role of melatonin in reducing oxidative stress in multiple sclerosis through its effect on SIRT1 and antioxidant enzymes

Results of multiple sclerosis :

Result	whereas melatonin treatment caused a pronounced increase in MnSOD mRNA expression and activity only in patients.
Mechanism/pathway	It appears that the antioxidant status is affected in PBMCs from MS patients and melatonin could improve impaired antioxidant defense in MS through up egulation of SIRT1, MnSOD and catalase, which might be important in MS management.