Basic information of Mir132 :

Official Symbol of Gene	Mir132
Species	Mus musculus
Entrez Gene ID	387150
Official Full Name	microRNA 132
Also known as	Mirn132; mir-132; mmu-mir-132
Gene Type	ncRNA
dbXrefs	Ensembl:ENSMUSG00000065537 miRBase:MI0000158; AllianceGenome:MGI:2676817
Map Location	11; 11 B5
Drug	2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57Bl/6J
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	23780851
Year	2013
Title	MicroRNA-132 suppresses autoimmune encephalomyelitis by inducing cholinergic anti-inflammation: a new Ahr-based exploration

Results of multiple sclerosis :

Result	Here, we show that TCDD induces cholinergic anti-inflammation in EAE mice by upregulating acetylcholinesterase-targeting miR-132. The expression of miR-132 was downregulated in CD4 cells and associated with EAE severity, while TCDD treatment attenuated EAE by inducing the miR-132/acetylcholinesterase module
Mechanism/pathway	Here, we show that TCDD induces cholinergic anti-inflammation in EAE mice by upregulating acetylcholinesterase-targeting miR-132. The expression of miR-132 was downregulated in CD4 cells and associated with EAE severity, while TCDD treatment attenuated EAE by inducing the miR-132/acetylcholinesterase module