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Basic information of Mt1 :

Official Symbol of Gene Mt1
Species Mus musculus
Entrez Gene ID 17748
Official Full Name metallothionein 1
Also known as MT-I; Mt-1
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000031765 AllianceGenome:MGI:97171
Map Location 8 C5; 8 46.34 cM
Drug Nimodipine
Interaction Type activator

Sample information of multiple sclerosis:

Descent Oli-Neu
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 36835129
Year 2023
Title Impact of the Voltage-Gated Calcium Channel Antagonist Nimodipine on the Development of Oligodendrocyte Precursor Cells

Results of multiple sclerosis :

Result Increased expression
Mechanism/pathway MT1 is capable of binding to free radicals and heavy metal ions and has neuroprotective potential in the CNS; Mt1/ and Mt2/ EAE mice display an increased number of CNS lesions.