Basic information of Ddit3 :

Official Symbol of Gene	Ddit3
Species	Mus musculus
Entrez Gene ID	13198
Official Full Name	DNA-damage inducible transcript 3
Also known as	chop; CHOP10; CHOP-10; gadd153; AltDDIT3
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000025408 AllianceGenome:MGI:109247
Map Location	10; 10 D3
Drug	Nimodipine
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	Oli-Neu
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	36835129
Year	2023
Title	Impact of the Voltage-Gated Calcium Channel Antagonist Nimodipine on the Development of Oligodendrocyte Precursor Cells

Results of multiple sclerosis :

Result	Increased expression
Mechanism/pathway	DDIT3 is activated when demyelination occurs. In the cuprizone mouse model, Ddit3-/- knockout mice show reduced demyelination.