Basic information of Tnf :

Official Symbol of Gene	Tnf
Species	Mus musculus
Entrez Gene ID	21926
Official Full Name	tumor necrosis factor
Also known as	DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000024401 AllianceGenome:MGI:104798
Map Location	17 B1; 17 18.59 cM
Drug	IFN-β therapy
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	SJL/J mice
Disease	EAE

Literature information of multiple sclerosis :

Pubmed ID	18471898
Year	2008
Title	Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result	Furthermore, inhibition of the pro-inflammatory cytokines TNF-α, IFN-γ and IL-12 and enhanced expression of the anti inflammatory cytokines IL-10, IL-4 and TGF-β was observed in CNS tissue.
Mechanism/pathway	pro-inflammatory cytokines