Basic information of Gsk3b :
| Official Symbol of Gene | Gsk3b |
| Species | Mus musculus |
| Entrez Gene ID | 56637 |
| Official Full Name | glycogen synthase kinase 3 beta |
| Also known as | GSK3; GSK-3; GSK-3beta; 7330414F15Rik; 8430431H08Rik |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000022812 AllianceGenome:MGI:1861437 |
| Map Location | 16; 16 B3 |
| Drug | lithium chloride |
| Interaction Type | inhibitor |
Sample information of multiple sclerosis:
| Descent | C57Bl/6J |
| Disease | experimental autoimmune encephalomyelitis |
Literature information of multiple sclerosis :
| Pubmed ID | 36526850 |
| Year | 2023 |
| Title |
Evaluation of in vivo lithium chloride effects as a GSK3 inhibitor on human adipose derived stem cells differentiation into oligodendrocytes and re |
Results of multiple sclerosis :
| Result | The use of Lithium Chloride can increase stem cells differentiation into oligodendrocytes and improve re-myelination in MS. |
| Mechanism/pathway | The application of neuroprotective agents in combination with stem cells is considered a potential effective treatment for multiple sclerosis (MS). |
