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Basic information of Ifng :

Official Symbol of Gene Ifng
Species Mus musculus
Entrez Gene ID 15978
Official Full Name interferon gamma
Also known as Ifg; If2f; IFN-g
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location 10 D2; 10 66.75 cM
Drug IFN-β therapy
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent SJL/J mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 18471898
Year 2008
Title Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result Furthermore, inhibition of the pro-inflammatory cytokines TNF-α, IFN-γ and IL-12 and enhanced expression of the anti inflammatory cytokines IL-10, IL-4 and TGF-β was observed in CNS tissue.
Mechanism/pathway pro-inflammatory cytokines