Basic information of Gna12 :

Official Symbol of Gene	Gna12
Species	Mus musculus
Entrez Gene ID	14673
Official Full Name	guanine nucleotide binding protein, alpha 12
Also known as	Galpha12
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000000149 AllianceGenome:MGI:95767
Map Location	5 G2; 5 79.3 cM
Drug	Fingolimod
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57Bl/6J
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	26980486
Year	2016
Title	The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration

Results of multiple sclerosis :

Result	In summary, we uncovered a broader cellular and therapeutic operation mode of FTY720, suggesting beneficial FTY720 effects also on CNS neurons during MS therapy and for treatment of other neurodegenerative diseases FTY720 effects also on CNS neurons during MS therapy and for treatment of other neurodegenerative diseases
Mechanism/pathway	Fingolimod (FTY720) is a new generation oral treatment for multiple sclerosis (MS). So far, FTY720 was mainly considered to target trafficking of immune cells but not brain cells such as neurons.