Home Details
| Official Symbol of Gene | Srf |
| Species | Mus musculus |
| Entrez Gene ID | 20807 |
| Official Full Name | serum response factor |
| Also known as | NA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000015605 AllianceGenome:MGI:106658 |
| Map Location | 17; 17 C |
| Drug | Fingolimod |
| Interaction Type | activator |
| Descent | C57Bl/6J |
| Disease | experimental autoimmune encephalomyelitis |
| Pubmed ID | 26980486 |
| Year | 2016 |
| Title | The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration |
| Result | In summary, we uncovered a broader cellular and therapeutic operation mode of FTY720, suggesting beneficial FTY720 effects also on CNS neurons during MS therapy and for treatment of other neurodegenerative diseases FTY720 effects also on CNS neurons during MS therapy and for treatment of other neurodegenerative diseases |
| Mechanism/pathway | Fingolimod (FTY720) is a new generation oral treatment for multiple sclerosis (MS). So far, FTY720 was mainly considered to target trafficking of immune cells but not brain cells such as neurons. |

2023,CopyRight © HMU. College of Bioinformatics Science and Technology, Harbin, China.