Basic information of Il12a :
| Official Symbol of Gene | Il12a |
| Species | Mus musculus |
| Entrez Gene ID | 16159 |
| Official Full Name | interleukin 12a |
| Also known as | p35; Ll12a; Il-12a; IL-12p35 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000027776 AllianceGenome:MGI:96539 |
| Map Location | 3 E1; 3 31.92 cM |
| Drug | IFN-β therapy |
| Interaction Type | inhibitor |
Sample information of multiple sclerosis:
| Descent | SJL/J mice |
| Disease | EAE |
Literature information of multiple sclerosis :
| Pubmed ID | 18471898 |
| Year | 2008 |
| Title | Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis |
Results of multiple sclerosis :
| Result | Furthermore, inhibition of the pro-inflammatory cytokines TNF-α, IFN-γ and IL-12 and enhanced expression of the anti inflammatory cytokines IL-10, IL-4 and TGF-β was observed in CNS tissue. |
| Mechanism/pathway | pro-inflammatory cytokines |
