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Basic information of FOXP3 :

Official Symbol of Gene FOXP3
Species Homo sapiens
Entrez Gene ID 50943
Official Full Name forkhead box P3
Also known as JM2; AIID; IPEX; PIDX; XPID; DIETER
Gene Type protein coding
dbXrefs Ensembl:ENSG00000049768 MIM:300292; AllianceGenome:HGNC:6106
Map Location Xp11.23
Drug rapamycin
Interaction Type activator

Sample information of multiple sclerosis:

Descent NA
Disease RRMS

Literature information of multiple sclerosis :

Pubmed ID 30219744
Year 2017
Title Promising effect of rapamycin on multiple sclerosis

Results of multiple sclerosis :

Result The expression rate of FOXP3 and GARP genes in regulatory T cells increased after the therapy which could favor the treatment of MS.
Mechanism/pathway The routine therapies for relapsing-remitting multiple sclerosis (RRMS) are common disease-modifying, yet are not effective in all patients.