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Basic information of LRRC32 :

Official Symbol of Gene LRRC32
Species Homo sapiens
Entrez Gene ID 2615
Official Full Name leucine rich repeat containing 32
Also known as GARP; CPPRDD; D11S833E
Gene Type protein coding
dbXrefs Ensembl:ENSG00000137507 MIM:137207; AllianceGenome:HGNC:4161
Map Location 11q13.5
Drug rapamycin
Interaction Type activator

Sample information of multiple sclerosis:

Descent NA
Disease RRMS

Literature information of multiple sclerosis :

Pubmed ID 30219744
Year 2017
Title Promising effect of rapamycin on multiple sclerosis

Results of multiple sclerosis :

Result The expression rate of FOXP3 and GARP genes in regulatory T cells increased after the therapy which could favor the treatment of MS.
Mechanism/pathway The routine therapies for relapsing-remitting multiple sclerosis (RRMS) are common disease-modifying, yet are not effective in all patients.