Basic information of IL4 :

Official Symbol of Gene	IL4
Species	Homo sapiens
Entrez Gene ID	3565
Official Full Name	interleukin 4
Also known as	BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000113520 MIM:147780; AllianceGenome:HGNC:6014
Map Location	5q31.1
Drug	interleukin (IL)-4 -producing HSV-1 g134.5 deletion viruses
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	NA
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	11420640
Year	2001
Title	Expression of interleukin-4 but not of interleukin-10 from a replicative herpes simplex virus type 1 viral vector precludes experimental allergic encephalomyelitis

Results of multiple sclerosis :

Result	The results indicate that the intracranial infection with IL-4-producing virus (1) precludes EAE symptoms, (2) protects the spinal cord from massive leukocyte infiltrations and (3) prevents demyelination and axonalloss
Mechanism/pathway	We have used interleukin (IL)-4 and -10-producing HSV-1 g134.5 deletion viruses in gene therapy of a BALB/c model of experimental allergic encephalomyelitis (EAE), a T cell-mediated demyelinating disease of the central nervous sys-tem