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Basic information of Il10 :

Official Symbol of Gene Il10
Species Mus musculus
Entrez Gene ID 16153
Official Full Name interleukin 10
Also known as CSIF; If2a; Il-10
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000016529 AllianceGenome:MGI:96537
Map Location 1 E4; 1 56.89 cM
Drug IFN-β therapy
Interaction Type activator

Sample information of multiple sclerosis:

Descent SJL/J mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 18471898
Year 2008
Title Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result Furthermore, inhibition of the pro-inflammatory cytokines TNF-α, IFN-γ and IL-12 and enhanced expression of the anti inflammatory cytokines IL-10, IL-4 and TGF-β was observed in CNS tissue.
Mechanism/pathway anti-inflammatory cytokines