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Basic information of IL-17A :

Official Symbol of Gene IL-17A
Species Homo sapiens
Entrez Gene ID 3605
Official Full Name interleukin 17A
Also known as IL17; CTLA8; IL-17; ILA17; CTLA-8; IL-17A
Gene Type protein coding
dbXrefs Ensembl:ENSG00000112115 MIM:603149; AllianceGenome:HGNC:5981
Map Location 6p12.2
Drug Vitamin D
Interaction Type activator

Sample information of multiple sclerosis:

Descent RRMS
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 26188623
Year 2015
Title Vitamin D supplementation up-regulates IL-6 and IL-17A gene expression in multiple sclerosis patients

Results of multiple sclerosis :

Result Significant up-regulation of IL-6 and IL-17A gene expression was shown under vitamin D treatment.
Mechanism/pathway Vitamin D regulates gene expression and affects target cell functions. IL-6 and IL-17A are pro-inflammatory cytokines associated with MS pathogenesis.