Basic information of ADA :

Official Symbol of Gene	ADA
Species	Homo sapiens
Entrez Gene ID	100
Official Full Name	adenosine deaminase
Also known as	ADA1
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000196839 MIM:608958; AllianceGenome:HGNC:186
Map Location	20q13.12
Drug	cladribine tablet
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	MS
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	33007809
Year	2020
Title	A Single Nucleotide ADA Genetic V ariant Is Associated to Central Inflammation and Clinical Presentation in MS: Implications for Cladribine Treatment

Results of multiple sclerosis :

Result	The selective targeting of the ADA pathway through cladribine tablet therapy could be effective in MS by acting on a pathogenically relevant biological mechanism.
Mechanism/pathway	The immune response homeostasis is crucially regulated by the activity of the enzyme adenosine deaminase (ADA), as evidenced in patients with genetic ADA deficiency and in those treated with cladribine tablets.