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Basic information of NCOA7 :

Official Symbol of Gene NCOA7
Species Homo sapiens
Entrez Gene ID 135112
Official Full Name nuclear receptor coactivator 7
Also known as ESNA1; TLDC4; ERAP140; NCOA7-AS; Nbla00052; Nbla10993; dJ187J11.3
Gene Type protein coding
dbXrefs Ensembl:ENSG00000111912 MIM:609752; AllianceGenome:HGNC:21081
Map Location 17q11.2
Drug Interferon b-1b
Interaction Type activator

Sample information of multiple sclerosis:

Descent MS
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 25330068
Year 2015
Title Induction of a Unique Isoform of the NCOA7 Oxidation Resistance Gene by Interferon b-1b

Results of multiple sclerosis :

Result We describe a new role for IFN-bs involving a mechanism of action that leads to an increase in resistance to inflammation-mediated oxidative stress.
Mechanism/pathway We demonstrate that interferon (IFN)-b-1b induces an alternative-start transcript containing the C-terminal TLDc domain of nuclear receptor coactivator protein 7 (NCOA7), a member of the OXR family of oxidation resistance proteins.