Basic information of Il-10 :

Official Symbol of Gene	Il-10
Species	Mus musculus
Entrez Gene ID	16153
Official Full Name	interleukin 10
Also known as	CSIF; If2a; Il-10
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000016529 AllianceGenome:MGI:96537
Map Location	1 E4; 1 56.89 cM
Drug	IFNb
Interaction Type	activator

Sample information of multiple sclerosis:

Descent	C57Bl/6J
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	22163016
Year	2011
Title	Type I IFN Promotes IL-10 Production from T Cells to Suppress Th17 Cells and Th17-Associated Autoimmune Inflammation

Results of multiple sclerosis :

Result	Together, results from this study suggest that IFNb may induce antigen-specific T cells to produce IL-10, which in turn negatively regulate Th17-mediate inflammatory and autoimmune response.
Mechanism/pathway	Whereas the immune system is essential for host defense against pathogen infection or endogenous danger signals,dysregulated innate and adaptive immune cells may facilitate harmful inflammatory or autoimmune responses