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Basic information of B4galt6 :

Official Symbol of Gene B4galt6
Species Mus musculus
Entrez Gene ID 56386
Official Full Name UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000056124 AllianceGenome:MGI:1928380
Map Location 18; 18 A2
Drug PDMP
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent NOD mice
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 25216636
Year 2014
Title Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation

Results of multiple sclerosis :

Result B4GALT5/6 inhibition suppresses astrocyte activation in EAE
Mechanism/pathway B4GALT5/6 inhibition by PDMP reduced the expression of demyelination-associated genes and increased the expression of remyelination-associated genes