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Basic information of Tgfb1 :

Official Symbol of Gene Tgfb1
Species Mus musculus
Entrez Gene ID 21803
Official Full Name transforming growth factor, beta 1
Also known as Tgfb; Tgfb-1; TGFbeta1; TGF-beta1
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000002603 AllianceGenome:MGI:98725
Map Location 7 A3; 7 13.98 cM
Drug IFN-β therapy
Interaction Type activator

Sample information of multiple sclerosis:

Descent SJL/J mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 18471898
Year 2008
Title Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result Furthermore, inhibition of the pro-inflammatory cytokines TNF-α, IFN-γ and IL-12 and enhanced expression of the anti inflammatory cytokines IL-10, IL-4 and TGF-β was observed in CNS tissue.
Mechanism/pathway anti-inflammatory cytokines