Basic information of Ehmt2 :

Official Symbol of Gene	Ehmt2
Species	Mus musculus
Entrez Gene ID	110147
Official Full Name	G9a; Bat8; NG36; KMT1C; D17Ertd710e
Also known as	17 B1; 17 18.45 cM
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000013787 AllianceGenome:MGI:2148922
Map Location	17 B1; 17 18.45 Cm
Drug	UNC0642
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57Bl/6J
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	35930635
Year	2020
Title	G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis

Results of multiple sclerosis :

Result	In line with these findings, we found a potent neuroprotective effect of pharmacological G9a inhibition manifesting in increased neuro-nal survival and improved clinical outcome in CNS inflammation.
Mechanism/pathway	G9a activity repressed anti-ferroptotic genes, diminished intracellular glutathione levels, and triggered the iron-dependent programmed cell death pathway ferroptosis