Details

Home Details


Basic information of Maf :

Official Symbol of Gene Maf
Species Mus musculus
Entrez Gene ID 17132
Official Full Name MAF bZIP transcription factor
Also known as c-maf; 2810401A20Rik; A230108G15Rik
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000055435 AllianceGenome:MGI:96909
Map Location 8 E1; 8 62.61 cM
Drug methyl butyrate (MB)
Interaction Type activator

Sample information of multiple sclerosis:

Descent C57Bl/6J
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 34786625
Year 2021
Title Methyl Butyrate Alleviates Experimental Autoimmune Encephalomyelitis and Regulates the Balance of Effector T Cells and Regulatory T Cells

Results of multiple sclerosis :

Result we found that MB treatment upregulated Maf gene expres-sion in mice, which explained its promotion of IL-10 secretion.
Mechanism/pathway MB Treatment Promotes Treg Development and IL10 Secretion in Draining Lymph Nodes of EAE Mice