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Basic information of Mbp :

Official Symbol of Gene Mbp
Species Mus musculus
Entrez Gene ID 17196
Official Full Name myelin basic protein
Also known as jve; mld; shi; Hmbpr; golli-mbp
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000041607 AllianceGenome:MGI:96925
Map Location 18 E3; 18 55.84 cM
Drug orexin-A (OX-A)
Interaction Type activator

Sample information of multiple sclerosis:

Descent C57Bl/6J
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 26857503
Year 2016
Title Role of orexin-A in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result Administration of OX-A or SB (30 nmol) in EAE induced mice in- creased and decreased the expression of MPB mRNA compared to the EAE group, respectively (F(8, 48) = 22.738; all p b 0.05)
Mechanism/pathway NA