Basic information of Il1r1 :

Official Symbol of Gene	Il1r1
Species	Mus musculus
Entrez Gene ID	16177
Official Full Name	interleukin 1 receptor, type I
Also known as	IL-iR; CD121a; CD121b; IL-1R1; Il1r-1; IL-1R-1; IL-1RT1; IL-1RT-1; IL-1R-alpha
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000026072 AllianceGenome:MGI:96545
Map Location	1 B; 1 18.81 Cm
Drug	interleukin-1 receptor antagonist
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	C57BL/6J
Disease	experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID	33358978
Year	2022
Title	Toll-like receptor 2 and 4 antagonism for the treatment of experimental autoimmune encephalomyelitis (EAE)-related pain

Results of multiple sclerosis :

Result	In support of these results, intrathecal interleukin-1 receptor antagonist reversed EAE-induced allodynia, both early and late after EAE induction.
Mechanism/pathway	NA