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Basic information of Elavl1 :

Official Symbol of Gene Elavl1
Species Mus musculus
Entrez Gene ID 15568
Official Full Name ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
Also known as HUR; Hua; 2410055N02Rik
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000040028 AllianceGenome:MGI:1100851
Map Location 8 A1.1; 8 2.0 cM
Drug anti-HuR antisense oligonucleotide (ASO)
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent C57BL/6J
Disease experimental autoimmune encephalomyelitis

Literature information of multiple sclerosis :

Pubmed ID 33200288
Year 2021
Title Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis

Results of multiple sclerosis :

Result Mice that received anti-HuR ASO exhibited improved EAE-related motor dysfunction, pain hypersensitivity, and body weight loss.
Mechanism/pathway NF-κB Activation Was Reduced by HuR Silencing