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Basic information of Ifnb1 :

Official Symbol of Gene Ifnb1
Species Mus musculus
Entrez Gene ID 15977
Official Full Name interferon beta 1, fibroblast
Also known as Ifb; IFNB; If1da1; IFN-beta
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000048806 AllianceGenome:MGI:107657
Map Location 4 C4; 4 41.91 Cm
Drug type I IFN mimetic
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 23110939
Year 2013
Title Type I IFN receptor controls activated TYK2 in the nucleus: implications for EAE therapy

Results of multiple sclerosis :

Result The observation that the type I IFN mimetic was therapeutically effective against EAE, but lacked the toxicity associated with the intact IFN suggests that the two events are not associated.
Mechanism/pathway The complex formation and the functional cytoplasmic activity of IFN truncations thus show similarities in complexity to that of steroid signaling