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Basic information of Pdgfa :

Official Symbol of Gene Pdgfa
Species Mus musculus
Entrez Gene ID 18590
Official Full Name platelet derived growth factor, alpha
Also known as PDGF-1
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000025856 AllianceGenome:MGI:97527
Map Location 5 G2; 5 77.65 cM
Drug IFN-β therapy
Interaction Type activator

Sample information of multiple sclerosis:

Descent SJL/J mice
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 18471898
Year 2008
Title Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Result In addition, mice receiving IFN-β had reduced apoptosis and increases in growth promoting factors including BDNF, CNTF, PDGF and VEGF.
Mechanism/pathway growth factors