Basic information of GPR183 :

Official Symbol of Gene	GPR183
Species	Homo sapiens
Entrez Gene ID	1880
Official Full Name	G protein-coupled receptor 183
Also known as	EBI2; Hebi2
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000169508 MIM:605741; AllianceGenome:HGNC:3128
Map Location	13q32.3
Drug	Natalizumab
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	RRMS
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	28052250
Year	2017
Title	EBI2 Expression and Function: Robust in Memory Lymphocytes and Increased by Natalizumab in Multiple Sclerosis

Results of multiple sclerosis :

Result	We observed that EBI2 is functionally expressed on memory CD4 T cells and is enhanced under natalizumab treatment.
Mechanism/pathway	These data suggest a significant role for EBI2 in human CD4 T cell migration, notably in patients with MS.