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Basic information of CNR2 :

Official Symbol of Gene CNR2
Species Homo sapiens
Entrez Gene ID 1269
Official Full Name cannabinoid receptor 2
Also known as CB2; CX5; CB-2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000188822 MIM:605051; AllianceGenome:HGNC:2160
Map Location 1p36.11
Drug interferon-β
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent RRMS
Disease MS

Literature information of multiple sclerosis :

Pubmed ID 25169051
Year 2015
Title Regulation of cannabinoid receptor gene expression and endocannabinoid levels in lymphocyte subsets by interferon-β: a longitudinal study in multiple sclerosis patients

Results of multiple sclerosis :

Result CB1 expression was elevated in all cell subsets
Mechanism/pathway The different expression of cannabinoid receptor genes and the increased level of AEA in lymphocytes point to a possible role of the cannabinoid system in MS immune response and its modulation by interferon.