Basic information of PPARG :

Official Symbol of Gene	PPARG
Species	Homo sapiens
Entrez Gene ID	5468
Official Full Name	peroxisome proliferator activated receptor gamma
Also known as	GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000132170 MIM:601487; AllianceGenome:HGNC:9236
Map Location	3p25.2
Drug	pioglitazone
Interaction Type	inhibitor

Sample information of multiple sclerosis:

Descent	N/A
Disease	MS

Literature information of multiple sclerosis :

Pubmed ID	16210596
Year	2005
Title	Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients

Results of multiple sclerosis :

Result	Effect of PIO treatment on PPAR-γDNA-binding activity and NF-kB DNA-binding activity in PBMCs from MS patients
Mechanism/pathway	In MS patients, pioglitazone-induced increase in PPAR-gamma DNA-binding activity and decrease in NF-kappaB DNA-binding activity was only observed in the absence of an acute MS relapse.