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Basic information of Tnf :

Official Symbol of Gene Tnf
Species Mus musculus
Entrez Gene ID 21926
Official Full Name tumor necrosis factor
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000024401 AllianceGenome:MGI:104798
Map Location 17 B1; 17 18.59 cM
Drug dTNFR
Interaction Type inhibitor

Sample information of multiple sclerosis:

Descent N/A
Disease EAE

Literature information of multiple sclerosis :

Pubmed ID 10679120
Year 2000
Title Gene therapy for chronic relapsing experimental allergic encephalomyelitis using cells expressing a novel soluble p75 dimeric TNF receptor

Results of multiple sclerosis :

Result These levels of dTNFR protein were biologically active and could significantly ameliorate both acute and relapsing EAE.
Mechanism/pathway This cell-based gene-vector approach is ideal for delivering proteins to the CNS and has particular relevance to the control of inflammatory CNS disease.